Danish Study Shows HRT cuts Heart Disease by 50% without Cancer Risk.

Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomized trial

After 10 years of randomized treatment, women receiving hormone replacement therapy early after menopause had a significantly reduced risk of mortality, heart failure, or myocardial infarction, without any apparent increase in risk of cancer, venous thromboembolism, or stroke.

  • HRT started early in postmenopausal women significantly reduces the risk of the combined endpoint of mortality, myocardial infarction, or heart failure
  • Postmenopausal women who started HRT early and used it for more than 10 years were not at significantly increased risk of breast cancer or stroke
  • For the subgroup of women who had undergone hysterectomy and who received unopposed 17-β-estradiol/control we found a significant reduction in the combined endpoint of mortality or breast cancer in the treatment group. This is in accordance with findings from the Women’s Health Initiative.

Download study in PDF: BMJ 2012;345:e6409 doi: 10.1136/bmj.e6409 (Published 9 October 2012)